2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-152614
    Antimalarial agent 19
    		Inhibitor
    Antimalarial agent 19 (compound 6e) is an antimalarial active agent. Antimalarial agent 19 has antimalarial activity for the blood stage of P. falciparum K1 and P. berghei with EC50 values of 0.3 µM, 15.3 µM, respectively. Antimalarial agent 19 has good aqueous solubility, intestinal permeability and microsomal stability compared to gamhepathiopine.
    Antimalarial agent 19
  • HY-111161
    GSK575594A
    		Inhibitor
    GSK575594A is a modulator of the nicotinic acetylcholine receptor (nAChR) in Ascaris suum. GSK575594A enhances muscle contractions induced by acetylcholine (ACh) by binding to the allosteric binding site between subunits within the transmembrane domain of nAChR. At a concentration of 3 μM, GSK575594A significantly increased the contraction induced by ACh in Ascaris suum (Emax increased from 1.19 g to 1.51 g). GSK575594A may be used in research within the field of antiparasitic studies.
    GSK575594A
  • HY-12784AS1
    Cycloguanil-d6 hydrochloride
    		Inhibitor
    Cycloguanil-d6 hydrochloride is the deuterium labeled Cycloguanil hydrochloride. Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.
    Cycloguanil-d<sub>6</sub> hydrochloride
  • HY-N0054R
    Osthole (Standard)
    		Inhibitor
    Osthole (Standard) is the analytical standard of Osthole. This product is intended for research and analytical applications. Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells.
    Osthole (Standard)
  • HY-146769
    Antimalarial agent 11
    		Inhibitor
    Antimalarial agent 11 (compound 1), a spirocyclic chromane, is a potent antimalarial agent. Antimalarial agent 11 exhibits excellent potency with an EC50 of 350 nM against the Chloroquine-resistant Dd2 strain. Antimalarial agent 11 has EC50s of 1.48 µM and 1.81 µM against D6 and ARC08-022 strains, respectively.
    Antimalarial agent 11
  • HY-B0978S1
    Diethyltoluamide-d7
    Diethyltoluamide-d7 is the deuterium labeled Diethyltoluamide[1]. Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects[2].
    Diethyltoluamide-d<sub>7</sub>
  • HY-161384
    WJM-715
    		Inhibitor
    WJM-715 is an antimalarial agent with an EC50 of 0.015 μM by trageting STAR-related lipid transfer protein (PfSTART1) with a KD of 14 nM.
    WJM-715
  • HY-B2029R
    Phosalone (Standard)
    		Inhibitor
    Phosalone (Standard) is the analytical standard of Phosalone. This product is intended for research and analytical applications.
    Phosalone (Standard)
  • HY-B1751F
    Quinidine gluconic acid
    		Inhibitor
    Quinate is an antiarrhythmic agent. Quinate is a potent, orally active, selective cytochrome P450db inhibitor. Quinate is also a K+ channel blocker with an IC50 of 19.9 μM, and can induce apoptosis. Quinate can be used for malaria research.
    Quinidine gluconic acid
  • HY-162155
    Diarctigenin
    		Inhibitor
    Diarctigenin is a selective Leishmania major dihydrofolate reductase-thymidylate synthase (LmDHFR-TS) inhibitor. Diarctigenin can be used for the research of tropical disease.
    Diarctigenin
  • HY-15648H
    GSK-J5 hydrochloride
    		Inhibitor
    GSK-J5 hydrochloride is a cell-permeable?ester derivative of?GSK J2 (HY-15648A), inactive. GSK-J5 hydrochloride is also an?isomer of GSK-J4 (HY-15648B) and often used as a negative group.
    GSK-J5 hydrochloride
  • HY-W268334
    1,2,3,4-Tetrahydronorharman-1-one
    		Inhibitor
    1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid with activity against infectious and tropical parasitic diseases from an Indonesian sponge.
    1,2,3,4-Tetrahydronorharman-1-one
  • HY-N8585
    Neoprocurcumenol
    		Inhibitor
    Neoprocurcumenol is a larvicidal compound that exerts significant toxicity on mosquito larvae with LC50 and LC 90 values of 13.69 and 23.92 ppm, respectively.
    Neoprocurcumenol
  • HY-B0508S
    Ornidazole-d5
    		Inhibitor
    Ornidazole-d5 is deuterium labeled Ornidazole.
    Ornidazole-d<sub>5</sub>
  • HY-128398
    CpCDPK1/TgCDPK1-IN-2
    		Inhibitor
    CpCDPK1/TgCDPK1-IN-2 (Compound 7r) is a CpCDPK1 and TgCDPK1 inhibitor with IC50 values of 12 and 5 nM, respectively. CpCDPK1/TgCDPK1-IN-2 can be used in the research of apicomplexan protozoa-related diseases, such as the research of T. gondii, C. parvum and C. hominus infection.
    CpCDPK1/TgCDPK1-IN-2
  • HY-149073
    TSC26
    		Inhibitor
    TSC26, a thiosemicarbazone, is a potent cruzipain (CZP) inhibitor with an IC50 of 175 nM, a pIC50 of 6.76 and a pKa of 6.6. TSC26 has the potential for parasitic diseases research.
    TSC26
  • HY-B1344R
    Oxantel pamoate (Standard)
    		Inhibitor
    Oxantel (pamoate) (Standard) is the analytical standard of Oxantel (pamoate). This product is intended for research and analytical applications. Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms.
    Oxantel pamoate (Standard)
  • HY-135666
    DHODH-IN-8
    		Inhibitor
    DHODH-IN-8 (Compound 27) is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50s of 0.13 μM and 47.4 μM, and Kis of 0.016 μM and 5.6 μM, respectively. DHODH-IN-8 has antimalarial activity.
    DHODH-IN-8
  • HY-N1584AR
    Halofuginone hydrobromide (Standard)
    		Inhibitor
    Halofuginone (hydrobromide) (Standard) is the analytical standard of Halofuginone (hydrobromide). This product is intended for research and analytical applications. Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.
    Halofuginone hydrobromide (Standard)
  • HY-N1219
    Stephanine
    		Inhibitor
    Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer.
    Stephanine
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.